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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TEK
All Species:
24.55
Human Site:
Y860
Identified Species:
45
UniProt:
Q02763
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02763
NP_000450
1124
125830
Y860
A
I
K
R
M
K
E
Y
A
S
K
D
D
H
R
Chimpanzee
Pan troglodytes
XP_520519
1124
125727
Y860
A
I
K
R
M
K
E
Y
A
S
K
D
D
H
R
Rhesus Macaque
Macaca mulatta
XP_001105270
1124
125731
Y860
A
I
K
R
M
K
E
Y
A
S
K
D
D
H
R
Dog
Lupus familis
XP_539652
1239
135146
Y976
A
I
K
M
L
K
E
Y
A
S
E
N
D
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q02858
1122
125682
Y858
A
I
K
R
M
K
E
Y
A
S
K
D
D
H
R
Rat
Rattus norvegicus
Q498D6
800
88690
R563
L
R
E
F
L
R
A
R
R
P
P
G
P
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505903
1124
124108
N875
A
L
S
R
K
A
K
N
N
P
D
P
T
I
Y
Chicken
Gallus gallus
P18460
806
89712
M569
R
A
R
R
P
P
G
M
D
Y
S
F
D
T
C
Frog
Xenopus laevis
O42127
802
89497
M565
K
A
R
R
P
P
G
M
D
Y
S
F
D
A
C
Zebra Danio
Brachydanio rerio
O73791
1116
122343
Y852
A
V
K
R
M
K
D
Y
A
S
Q
D
D
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
Y492
P
L
Y
V
I
V
E
Y
A
P
H
G
N
L
K
Honey Bee
Apis mellifera
XP_396649
796
90178
A559
L
Y
V
V
V
E
F
A
P
H
G
N
L
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26614
972
110463
R735
L
R
D
F
L
R
S
R
R
P
P
E
E
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.4
44
N.A.
92.7
25.7
N.A.
69.4
24.2
26.1
52.7
N.A.
23.9
25.2
N.A.
22.6
Protein Similarity:
100
99.1
99.1
57.9
N.A.
96
39.6
N.A.
77.8
40.2
40.7
67.9
N.A.
38.2
41
N.A.
39.5
P-Site Identity:
100
100
100
73.3
N.A.
100
0
N.A.
13.3
13.3
13.3
80
N.A.
20
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
20
N.A.
26.6
20
20
100
N.A.
46.6
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
16
0
0
0
8
8
8
54
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% C
% Asp:
0
0
8
0
0
0
8
0
16
0
8
39
62
8
8
% D
% Glu:
0
0
8
0
0
8
47
0
0
0
8
8
8
0
8
% E
% Phe:
0
0
0
16
0
0
8
0
0
0
0
16
0
0
0
% F
% Gly:
0
0
0
0
0
0
16
0
0
0
8
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
47
0
% H
% Ile:
0
39
0
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
47
0
8
47
8
0
0
0
31
0
0
0
8
% K
% Leu:
24
16
0
0
24
0
0
0
0
0
0
0
8
8
8
% L
% Met:
0
0
0
8
39
0
0
16
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
16
8
0
0
% N
% Pro:
8
0
0
0
16
16
0
0
8
31
16
8
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
16
16
62
0
16
0
16
16
0
0
0
0
8
47
% R
% Ser:
0
0
8
0
0
0
8
0
0
47
16
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% T
% Val:
0
8
8
16
8
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
54
0
16
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _